Stress Anxiety and Sexual Dysfunction in Women Undergoing Infertility Treatment
DOI:
https://doi.org/10.53350/pjmhs20231709264Keywords:
infertility; anxiety; stress; sexual dysfunctionAbstract
Background: Infertility and its treatment represent a major life stressor for women, with profound psychological and interpersonal consequences. Recurrent treatment cycles, uncertainty regarding outcomes, financial burden, and sociocultural expectations contribute to heightened stress and anxiety. These psychological factors may negatively influence sexual function, further impairing emotional well-being and quality of life during infertility management.
Objectives: To determine the frequency of stress, anxiety, and sexual dysfunction among women undergoing infertility treatment and to evaluate the association between psychological distress and impairment in sexual function.
Methodology: This cross-sectional study will be conducted at a tertiary care infertility centre. Women undergoing medical or assisted reproductive treatments will be enrolled using non-probability consecutive sampling. Psychological distress will be assessed using the Perceived Stress Scale (PSS) and the anxiety subscale of the Hospital Anxiety and Depression Scale (HADS-A). Sexual function will be evaluated using the Female Sexual Function Index (FSFI). Sociodemographic characteristics, infertility duration, and treatment-related variables will be recorded. Data will be analysed using appropriate descriptive and inferential statistical tests.
Results: 120 women undergoing infertility treatment, 78.3% reported moderate to high perceived stress and 36.7% had clinically significant anxiety. Sexual dysfunction (FSFI <26.55) was observed in 68.3% of participants and was significantly associated with higher stress, anxiety levels, longer infertility duration, and advanced treatment modalities (p < 0.05).
Conclusion: Psychological distress and sexual dysfunction are common among women undergoing infertility treatment and are significantly interrelated. Incorporating routine psychological screening and integrated psychosocial support into infertility care may improve sexual health, emotional well-being, and overall treatment experiences.
References
Cao D, Bai C, Zhang G. Psychological Distress Among Infertility Patients: A Network Analysis. Frontiers in psychology. 2022;13:906226.
Djaali W, Abdurrohim K, Helianthi DR. Management of Acupuncture as Adjuvant Therapy for In Vitro Fertilization. Medical acupuncture. 2019;31(6):361-5.
Dong M, Tao Y, Wu S, Kong L, Zhou F, Tan J. Changes in sexual behaviour, anxiety symptoms, and quality of couple relationship of patients with infertility during the COVID-19 lockdown. Journal of assisted reproduction and genetics. 2022;39(2):493-504.
Emokpae MA, Brown SI. Effects of lifestyle factors on fertility: practical recommendations for modification. Reproduction & fertility. 2021;2(1):R13-r26.
Haimovici F, Anderson JL, Bates GW, Racowsky C, Ginsburg ES, Simovici D, et al. Stress, anxiety, and depression of both partners in infertile couples are associated with cytokine levels and adverse IVF outcome. American journal of reproductive immunology (New York, NY : 1989). 2018;79(4):e12832.
Järvholm S. [Psychological aspects of infertility]. Lakartidningen. 2022;119.
Moshfeghy Z, Tahari S, Janghorban R, Najib FS, Mani A, Sayadi M. Association of sexual function and psychological symptoms including depression, anxiety and stress in women with recurrent vulvovaginal candidiasis. Journal of the Turkish German Gynecological Association. 2020;21(2):90-6.
Pozza A, Dèttore D, Coccia ME. Depression and Anxiety in Pathways of Medically Assisted Reproduction: The Role of Infertility Stress Dimensions. Clinical practice and epidemiology in mental health : CP & EMH. 2019;15:101-9.
Stevenson EL, Cebert M, Silva S. Stress and Anxiety in Couples Who Conceive via In Vitro Fertilization Compared With Those Who Conceive Spontaneously. Journal of obstetric, gynecologic, and neonatal nursing : JOGNN. 2019;48(6):635-44.
Woods BM, Patrician PA, Fazeli PL, Ladores S. Infertility-related stress: A concept analysis. Nursing forum. 2022;57(3):437-45.
Boivin J, Koert E, Harris T, O'Shea L, Perryman A, Parker K, et al. An experimental evaluation of the benefits and costs of providing fertility information to adolescents and emerging adults. Human reproduction (Oxford, England). 2018;33(7):1247-53.
Brasil DL, Montagna E, Trevisan CM, La Rosa VL, Laganà AS, Barbosa CP, et al. Psychological stress levels in women with endometriosis: systematic review and meta-analysis of observational studies. Minerva medica. 2020;111(1):90-102.
Caniklioglu M, Firat F, Oztekin Ü, Sari S, Selmi V, Işikay L. Evaluation of male sexual parameters in infertile couples with a history of abortion. Revista internacional de andrologia. 2022;20 Suppl 1:S48-s54.
Cocchiaro T, Meneghini C, Dal Lago A, Fabiani C, Amodei M, Miriello D, et al. Assessment of sexual and emotional distress in infertile couple: validation of a new specific psychometric tool. Journal of endocrinological investigation. 2020;43(12):1729-37.
Gaskins AJ, Sundaram R, Buck Louis GM, Chavarro JE. Predictors of Sexual Intercourse Frequency Among Couples Trying to Conceive. The journal of sexual medicine. 2018;15(4):519-28.
Kiesswetter M, Marsoner H, Luehwink A, Fistarol M, Mahlknecht A, Duschek S. Impairments in life satisfaction in infertility: Associations with perceived stress, affectivity, partnership quality, social support and the desire to have a child. Behavioral medicine (Washington, DC). 2020;46(2):130-41.
Mińko A, Turoń-Skrzypińska A, Rył A, Bargiel P, Hilicka Z, Michalczyk K, et al. Endometriosis-A Multifaceted Problem of a Modern Woman. International journal of environmental research and public health. 2021;18(15).
Ramgir SS, Renu K, Vellingiri B, George A, Tirupapuliyur D, Thiagarajan P, et al. Phytomedicinal therapeutics for male infertility: critical insights and scientific updates. Journal of natural medicines. 2022;76(3):546-73.
Song S, Chen N, Duan YP, Kang J, Deng S, Pan HX, et al. Anxiety symptoms in patients with Mayer-Rokitansky-Küster-Hauser syndrome: a cross-sectional study. Chinese medical journal. 2020;133(4):388-94.
Stanhiser J, Steiner AZ. Psychosocial Aspects of Fertility and Assisted Reproductive Technology. Obstetrics and gynecology clinics of North America. 2018;45(3):563-74.
Li CC, Feng TH. [Talk About Psychological Distress and Support in Women With Gynecological Cancer: NOT Just the Disease]. Hu li za zhi The journal of nursing. 2022;69(4):20-6.
Omani-Samani R, Amini P, Navid B, Sepidarkish M, Maroufizadeh S, Almasi-Hashiani A. Prevalence of Sexual Dysfunction among Infertile Women in Iran: A Systematic Review and Meta-analysis. International journal of fertility & sterility. 2019;12(4):278-83.
Silwal A, Thapa B. Prevalence of Domestic Violence among Infertile Women attending Subfertility Clinic of a Tertiary Hospital. JNMA; journal of the Nepal Medical Association. 2020;58(226):372-6.
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Copyright (c) 2023 Muhammad Muslim Khan, Fatima, Naila, Izaz Jamal, Ijaz Gul, Pirzada Muneeb

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