Outcomes of Trabeculectomy with Mitomycin C in Glaucoma Patients: A Study on the Mean Change in Intraocular Pressure in 200 Patients

Abstract

Objective: This study aims to evaluate the outcomes of trabeculectomy with Mitomycin C (MMC) in terms of mean change in intraocular pressure (IOP) in 200 glaucoma patients.

Methods: A cohort of 200 glaucoma patients undergoing trabeculectomy with MMC was analyzed. Preoperative and postoperative IOP measurements were taken at intervals (1 month, 3 months, 6 months, and 12 months). Demographic variables, surgical complications, and postoperative interventions were also recorded.

Results: The mean preoperative IOP was 26.4 mmHg, which decreased significantly to 12.3 mmHg at 12 months post-surgery. The success rate in achieving target IOP (< 21 mmHg) was 87%. The incidence of postoperative complications such as hypotony, infection, and bleb leaks was low.

Conclusion: Trabeculectomy with MMC is highly effective in reducing IOP in glaucoma patients, with a significant mean change in IOP from preoperative to postoperative stages. MMC plays a key role in improving surgical success by preventing scarring and bleb failure.

Keywords: Trabeculectomy, Mitomycin C, intraocular pressure, glaucoma, surgical outcomes, postoperative complications.