Treatment Efficacy of Vernal Keratoconjunctivitis with 0.1 Percent Fluorometholone and 0.05 Percent Cyclosporine

Authors

  • Asna Tahir, Syed Shujaat Ali Shah, Muhammad Awais Ashraf, Muhammad Naeem, Lt Col Ayyaz Hussain Awan, Muhammad Zia Iqbal

DOI:

https://doi.org/10.53350/pjmhs2023172941

Abstract

Objective: The purpose of this study was to evaluate the efficacy of two common treatments for vernal keratoconjunctivitis: fluorometholone (0.1%) and cyclosporine (0.05%).

Study Design: Comparative/prospective study

Methods: Total 86 patients of vernal keratoconjunctivitis were included in this study. Two groups were equally created, group I received fluorometholone (0.1%) in 43 cases and group II received cyclosporine (0.05%)in 43 cases. To find the significant value, chi-square and unpaired t test procedures were employed.

Results: There were 52 (60.5%) males and 34 (39.5%) females among all cases. There were 45 (52.3%) cases had age 5-10 years, 25 (29.1%) cases had age 11-15 years and 16 (18.6%) cases had age 16-20 years. Among all, itching and redness were the most common signs/symptoms. Frequency of efficacy in group I was 39 (90.7%) and in group II efficacy was found in 31 (72.1%) cases with p value <0.003. Frequency of systemic allergy was higher in group I as compared to group II <0.002.

Conclusion: According to these findings, fluorometholone might be an improved option for treating severe vernal keratoconjunctivitis. It is important to take systemic allergy links into account when treating.

Keywords: Cyclosporine, Fluorometholone, Vernal Keratoconjunctivitis

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How to Cite

Asna Tahir, Syed Shujaat Ali Shah, Muhammad Awais Ashraf, Muhammad Naeem, Lt Col Ayyaz Hussain Awan, Muhammad Zia Iqbal. (2023). Treatment Efficacy of Vernal Keratoconjunctivitis with 0.1 Percent Fluorometholone and 0.05 Percent Cyclosporine. Pakistan Journal of Medical & Health Sciences, 17(02), 941. https://doi.org/10.53350/pjmhs2023172941